stephen-guilfoy
Team TFS
Team TFS
since ‎03-09-2015
‎07-22-2021

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Big Money in Big Pharma

04-08-2016
Like many people, I’ve been astounded by the cost of some specialist drugs. Before I worked with this industry, I consumed the tabloid headlines aghast at treatments that could cost the patient or their insurer thousands or even hundreds of thousands...

Why Have High Performance When You Can Have Ultra-High Performance?

11-02-2015
Liquid chromatography plays an extremely important part in the development and production of biotherapeutic drugs. From separation of large quantities of antibodies in cell culture media to minute quantities of product from biological fluids during c...

Ahoy! Do I Need Satellite Navigation for my Peptide Map?

10-09-2015
My colleague Karen Thorsen’s recent blog post about super-fast protein digestion (link to blog post) got me thinking about the peptide mapping process, how hard it is, and how it could be made easier. And, perhaps more to the point, why is peptide ma...

Antibodies Attack! What Happens When Biotherapeutics Go Bad?

07-31-2015
It’s well known that biotherapeutic drugs (also known as biologics) are more difficult to produce consistently than our old friends, small molecule drugs. And, manufacturers spend untold amounts of money trying to make sure that each batch of biologi...

Antibodies: Tough Killers or Big Softies?

05-14-2015
Quick question: what is a monoclonal antibody? What does it really do? If you already work in biotherapeutics, or if your high-school biology is within memory then you may know. But for the rest of us, do we really know? I’m a physicist by training s...
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