Aaron_TFS
Team TFS
Team TFS
since ‎05-03-2021
‎04-26-2023

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  • 38 Posts
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Advances in genetics and bioengineering have enabled the development of gene therapy to treat diseases caused by recessive gene disorders, acquired genetic diseases, and some viral infections. Technologies for the manufacture and analysis of gene the...
Knowing the genome packaging efficiency during adeno-associated virus (AAV) manufacturing is a crucial step toward the successful clinical application of next-generation biotherapeutics. In recent years, recombinant AAV production has been steadily o...
Production of recombinant adeno-associated viruses (AAVs) for the purpose of gene therapy is challenging and requires various analytical assays to monitor product quality attributes (PQAs) such as product titer. Due to low production yields, it’s imp...
This is the fourth blog post in the Biopharmaceutical Basics series. Over the past 30 years, noteworthy progress has been made in the field of oligonucleotide therapeutics, beginning with antisense oligonucleotides (ASOs) and aptamers, followed by si...
This is the third blog post in the Biopharmaceutical Basics series. Sometimes the whole or part of a gene is defective or missing from birth. This is typically referred to as a genetically inherited mutation. In addition, healthy genes can change (mu...