Topics with Label: Method optimization

HPLC Troubleshooting Tips: Limit of Detection

Do you know how detector settings and parameters influence the limit of detection (LOD)? It is all about the Signal-to-Noise Ratio! Read more in my Blog: Why Signal-to-Noise Ratio Determines the Limit of Detection

HPLC Troubleshooting Tips: Precipitation of Buffers

Have you ever seen pressure fluctuations or retention time shifts in your HPLC that go away as suddenly as they appeared? Do you use buffers in your HPLC application? If you answered yes, read this Blog: Precipitation of Buffers in Gradient Elution M...

Looking for trace level compounds? Or maybe just highly reproducible data

Did you know that your choice in vial/well plate can also contribute to whether you see your analytes. Some analytes are more prone to adsorbing to glassware than others...Some analytes are susceptible to degradation in the presence of light Why not ...

Liquid Chromatography

Forum Posts

HPLC Troubleshooting Tips: Limit of Detection

HPLC Troubleshooting Tips: Precipitation of Buffers

Looking for trace level compounds? Or maybe just highly reproducible data

Brands

Shopping Tools

eSolutions

Support

Thermo Fisher Scientific