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Knowledge Base Articles
On-demand Webinar: Discover what is Hiding in your Proteomics Data
The field of mass spectrometry has advanced tremendously over the last decade on both the hardware as well as the software side. Nevertheless, we still do not use the full capacity of the acquired proteomic data and several layers of information get ...
On-demand Webinar: Comprehensive and Easy to use Workflows for Oligonucleotide Sequence Confirmation
Workflows for the analysis oligonucleotides by high resolution LCMS to support therapeutic drug development can often cover a wide range of modalities, ranging from heavily modified sequences to very large chains that exceed more than 50 nucleotide b...
Characterization of Biotherapeutic Beasts by Mass Spectrometry On-demand Webinar
The market of biologics in Biopharma companies is in constant evolution and moved away in the last few years from classical monoclonal antibody to proteins that are more difficult to analyze, such as therapeutics proteins, antibody drug/molecule conj...
Oligonucleotide analysis, new practical advances and tips to a mature technique
Learn how to achieve superior reversed phase oligonucleotide separations using the unique chemistry designed for analysis of oligonucleotides and double-stranded (ds) DNA/RNA fragments using LC-UV or LC-MS. Here we will focus on Specifically designed...
Robust and sensitive separation of mAbs and intact proteins using capillary chromatography by LC-MS
Learn how to utilize superior resolving power to achieve in depth characterization of therapeutic antibodies at protein, subunit and peptide level using the novel capillary Thermo Scientific™ MabPac™ RP column in in either stand-alone or integrated E...
Optimizing LC-MS Methods for Oligonucleotide Analysis
Liquid Chromatography-Mass Spectrometry (LC-MS) assays have been one of the main choices for oligonucleotide analysis because it is possible to quantify and identify the oligonucleotide and its impurities in a single analysis. Each stage of the analy...
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