Metabolomics presents unique challenges in terms of data acquisition,
data processing, data standardization, statistical analyses, and
identification of unknowns. Robust and precise analytical methods are
essential to metabolomics, but data acquisiti...
The aim of untargeted metabolomics is to comprehensively profile the
full range of metabolites present within a biological sample. Several
experimental factors strongly influence success: extraction method,
separation strategy, ionization mechanism, ...
Mass spectrometry plays a key role in the translational proteomics
pipeline: whereas continuous improvements in technologies at the
discovery side increase qualitative and quantitative coverage of the
entire proteoform diversity, ongoing optimization...