The field of mass spectrometry has advanced tremendously over the last
decade on both the hardware as well as the software side. Nevertheless,
we still do not use the full capacity of the acquired proteomic data and
several layers of information get ...
Workflows for the analysis oligonucleotides by high resolution LCMS to
support therapeutic drug development can often cover a wide range of
modalities, ranging from heavily modified sequences to very large chains
that exceed more than 50 nucleotide b...
The market of biologics in Biopharma companies is in constant evolution
and moved away in the last few years from classical monoclonal antibody
to proteins that are more difficult to analyze, such as therapeutics
proteins, antibody drug/molecule conj...
Learn how to achieve superior reversed phase oligonucleotide separations
using the unique chemistry designed for analysis of oligonucleotides and
double-stranded (ds) DNA/RNA fragments using LC-UV or LC-MS. Here we
will focus on Specifically designed...
Learn how to utilize superior resolving power to achieve in depth
characterization of therapeutic antibodies at protein, subunit and
peptide level using the novel capillary Thermo Scientific™ MabPac™ RP
column in in either stand-alone or integrated E...
Liquid Chromatography-Mass Spectrometry (LC-MS) assays have been one of
the main choices for oligonucleotide analysis because it is possible to
quantify and identify the oligonucleotide and its impurities in a single
analysis. Each stage of the analy...