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High sensitivity and throughput LCMS for single-cell proteomics and low sample amounts

The state-of-the-art low-flow Thermo ScientificTM Vanquish™ Neo liquid chromatography (LC) system, coupled with electrospray ionization-based Thermo ScientificTM Orbitrap™ Exploris™ 480 mass spectrometry (MS) technologies, can provide the sensitivity...

Targeted proteomic characterization of the AKT/mTOR pathway through analysis of clinically derived samples

Rowan Matney1, Kratika Singhal1, Fang Liu1, Sarah Trusiak2, Emily Chen2, Ryan D. Leib1, Allis S. Chien1International Hupo 2020To tackle questions of differential protein expression in the expanding phosphoproteome, one emerging strategy is the target...

Extending cross-linking analyses with XlinkX/PD to low FDR-rates and structural interpretation

Frank Berg1, Kai Fritzemeier1, Bernard Delanghe1, Rosa Viner2, Richard A. Scheltema3,4International Hupo 2020Crosslinking mass-spectrometry (XL-MS) has become a powerful structural biology application for protein structure determination and protein i...

Fully automated sample processing and analysis workflow for low-input label-free proteome profiling

Yiran Liang, Hayden Acor, Michaela A. McCown, Andikan J. Nwosu, Hannah Boekweg, Nathaniel B. Axtell, Thy Truong, Yongzheng Cong, Samuel H. Payne, Ryan T. KellyInternational Hupo 2020Deep proteome profiling of sub microgram and nanogram samples is sti...

In-depth single-cell proteome profiling of neuronal subtypes from human spinal tissue

Santosh A. Misal1, Yongzheng Cong1, Amanda J. Guise2, Khatereh Motamedchaboki3, Yiran Liang1, Thy Truong1, Romain Huguet3, Daniel Lopez-Ferrer3, Edward D. Plowey3, Ying Zhu4, Edward D. Plowey2, Ryan T. Kelly1International Hupo 2020Single-cell analysi...

Monitoring liver regeneration in individuals from living donor transplantation cases. A serum proteomics study.

Lorena Carmona-Rodríguez1, Aaron S. Gajadhar2, Antonio Ramos-Fernández3, Iker Uriarte4, Bruno Sangro5, Josemaria Argemi5, Jose Ignacio Herrero5, Daniel López-Ferrer2, Matías A. Ávila4, Fernando J. Corrales1International Hupo 2020Living donor liver tr...

Toward a Single Comprehensive Assay for Protein Expression of the Human Kinome

Robert Sprung1, Aaron Gajadhar2a, Michael East3, Petra Gilmore1, Daniel Lopez Ferrer2a, Bhavin Patel2b, Sebastien Gallien2c, Dennis Goldfarb1, Ben Major1, Gary L. Johnson3, R. Reid Townsend1International Hupo 2020The human kinome is comprised of 518 ...

Scientific Library

Knowledge Base Articles

High sensitivity and throughput LCMS for single-cell proteomics and low sample amounts

Targeted proteomic characterization of the AKT/mTOR pathway through analysis of clinically derived samples

Extending cross-linking analyses with XlinkX/PD to low FDR-rates and structural interpretation

Fully automated sample processing and analysis workflow for low-input label-free proteome profiling

In-depth single-cell proteome profiling of neuronal subtypes from human spinal tissue

Monitoring liver regeneration in individuals from living donor transplantation cases. A serum proteomics study.

Toward a Single Comprehensive Assay for Protein Expression of the Human Kinome

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