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Knowledge Base Articles

Expanding the Depth and Sensitivity of Cross-Link Identification by Differential Ion Mobility Using High-Field Asymmetric Waveform Ion Mobility Spectrometry

Lennart Schnirch, Michal Nadler-Holly, Siang-Wun Siao, Christian K. Frese, Rosa Viner, and Fan LiuIn cross-linking mass spectrometry (XL-MS), the depth and sensitivity of cross-link detection is often limited by the low abundance of cross-links compa...

Top-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer

Luca Fornelli a,1 , Daniel Ayoub a,2 , Konstantin Aizikov b , Xiaowen Liu c,d , Eugen Damoc b , Pavel A. Pevzner e , Alexander Makarov b , Alain Beck f , Yury O. Tsybin a,g, ⁎Journal of Proteomics Available online 27 February 2017The increasing impor...

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