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Extending cross-linking analyses with XlinkX/PD to low FDR-rates and structural interpretation

Frank Berg1, Kai Fritzemeier1, Bernard Delanghe1, Rosa Viner2, Richard A. Scheltema3,4International Hupo 2020Crosslinking mass-spectrometry (XL-MS) has become a powerful structural biology application for protein structure determination and protein i...

Getting start on XlinkX 2.5 for Proteome Discoverer 2.5

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Expanding the Depth and Sensitivity of Cross-Link Identification by Differential Ion Mobility Using High-Field Asymmetric Waveform Ion Mobility Spectrometry

Lennart Schnirch, Michal Nadler-Holly, Siang-Wun Siao, Christian K. Frese, Rosa Viner, and Fan LiuIn cross-linking mass spectrometry (XL-MS), the depth and sensitivity of cross-link detection is often limited by the low abundance of cross-links compa...

An urgent need for expanded virus research

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First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

Claudio Iacobucci,a,# Christine Piotrowski,a,# Ruedi Aebersold,b,c Bruno C. Amaral,d Philip Andrews,e Katja Bernfur,q Christoph Borchers,f,g,h,i Nicolas I. Brodie,f James E. Bruce,j Yong Cao,o Stephane Chaignepain, ́ k Juan D. Chavez,j Stephane Clave...

Evaluation of FAIMS Technology for Mass Spec Analysis of Chemical Cross-linked Peptides

Rosa Viner1; Leigh A Foster2; Ryan D. Bomgarden2; Michael W. Belford1; Satendra Prasad1; Romain Huguet1; Eloy R. Wouters1 ASMS 2019 PosterPurpose: To evaluate widely used enrichment/fractionation techniques and the newly developed High Field Asymmetr...

Thermo Scientific Orbitrap MS Workshop: Smarter. Faster. Simpler. Becoming an Orbitrap Power User.

Thermo Scientific and Customer PresentersASMS 2019 Orbitrap Power User MeetingExcited by the power and potential of your Thermo Scientific Orbitrap-based mass spectrometer? From small molecules to large, receive training on system calibration and mai...

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