Scientific Library

Changes from EPA Method 218.6 to 218.7 Yield Improved Detection Limits for Hexavalent Chromium

Presentation of modifications tothe existing US EPA method 218.6 toallow sufficient sensitivity for determininghexavalent chromium

LCGC Executive Summary: Multi-residue analysis of pesticides by GC-HRMS

In this paper, we discuss the use of the Thermo Scientific™ GC Orbitrap™ system for multi-residue analysis of pesticides. We begin with a brief introduction to the challenge, followed by a description of the operation and then we will highlight the a...

Safety Assessment of Food Contact Materials: The Role of High-Resolution Mass Spectrometry in the Comprehensive Analysis of the Total Migrate

This white paper describes the issue of chemicals migrating into food from packaging materials, the need to assess the safety of those chemicals that migrate, and the role that high resolution mass spectrometry has to play in the related analysis.

Analytical Challenges for Pesticide Residue Analysis in Food: Sample Preparation, Processing, Extraction and Cleanup

White paper discussing the analytical challenges for pesticide residue analysis in food.

White Paper: Mass Spectral Studies of Polypropylene Chromatographic Well Plates

This white paper identifies how low extraction 96-well deep well plates are suitable for use with high sensitivity chromatographic methods.Mass spectral data shows that persistent contamination from a range of compounds found in the raw polymer maste...

Extractables and Leachables: Regulatory requirements for vaccine and biologic products

Including extractables and leachables from packaging components in an overall assessment of product risk is important in ensuring patient safety. A partnership with a trusted supplier that also provides extractables and leachables testing alleviates ...

Dr. John Koomen on Data-Independent Analysis and Targeted MS/MS Quantification of Biomarkers

Clinical research applications of proteomics increasingly rely on MS-based approaches. Biomarker discovery, development, verification, validation, and quantification are all accessed using these approaches. Although different data collection modes ex...

Triumphs and Challenges of High-Resolution Mass Spectrometry in Comprehensive Pesticide Residue Screens

Evaluation of Q Exactive LC-MS for Pesticide Residues in Fruits and Vegetables featuring Amadeo Fernandez-Alba from the University of Alméria, Spain

Pesticide Residue Analysis: Tips and Tricks for the Whole Workflow eBook

Pesticide residue analysts are challenged to detect, identify, and quantify hundreds of different pesticides from different compound classes at low ng/g concentrations in a large number of diverse sample types with a fast turnaround, often within 24 ...

Determining Nitrosamines Using GC-MS/MS with Electron Ionization

Traditionally, nitrosamines have been analyzed by an ion trap in the MS/MS mode, using chemical ionization (CI) to provide a “soft” ionization of the precursor ion (e.g., U.S. Environmental Protection Agency (EPA) Method 521). Most of these methods r...

Mass Spectral Studies of Polypropylene Chromatographic Well Plates

This study has been undertaken to identify low extraction 96-well deep well plates that are suitable for use with high sensitivity chromatographic methods.Mass spectral data shows that persistent contamination from a range of compounds found in the r...

HRMS in Clinical Research: from Targeted Quantification to Metabolomics

In this white paper, Dr. Rochat of CHUV will discuss the use of new, affordable HRMS instruments in quantitative clinical research analyses, demonstrating the sensitivity and selectivity of these instruments for this work. Examples of clinical resear...

The Power of High Resolution Accurate Mass Using Orbitrap Based GC-MS

The Thermo ScientificTM Q ExactiveTM GC hybrid quadrupole-Orbitrap mass spectrometer is a benchtop instrument, designed to bring the power of Orbitrap high-resolution, accurate-mass (HR/AM) to gas chromatographic (GC) separations.Obtaining mass spect...

Orbitrap Fusion MS for Glycan and Glycopeptide Analysis

The introduction of the Orbitrap Fusion MS provides a giant step forward for the glycomics and glycoproteomics community. The innovative instrument design contains new functionalities, including a mass selecting quadrupole coupled to both a linear io...

Understanding New USP Chapter for Trace Elemental Contaminants in Dietary Supplements and Nutraceutical Products

Understanding New USP Chapter for Trace Elemental Contaminants in Dietary Supplements and NutraceuticalProducts

Fast and Sensitive GC-MS/MS Analysis of Trace Chemicals

This White Paper shows how the unique technology in the EvoCell collision cell of the TSQ 8000 Evo GC-MS/MS shortens method development and allows faster turnaround time, saving time and money.

Accelerated Solvent Extraction for Additives in Polymer Materials

Accelerated solvent extraction is a sample preparation technique that is beneficial to laboratories extracting additives from polymermaterials. This technique uses elevated temperature and pressure to improve extraction efficiency for samples that ar...

Improving Sample Preparation Workflow with Automated Evaporation

The Thermo Scientific™ Rocket™ Evaporator system automates theconcentration process following extraction using a Thermo Scientific™ Dionex™ ASE™ Accelerated Solvent Extractor system or a Thermo Scientific™ AutoTrace™ 280 Solid-Phase Extraction instru...

Measurement and Control of Copper Additives in Electroplating Baths by High-Performance Liquid Chromatography

Recently, copper has been incorporated into the fine wires (down to nanometer widths) in integrated chips, requiring careful control of the plating process.

Separation and Identification of Polar Metabolites by Ion Chromatography Coupled with High-Resolution Accurate-Mass Spectrometry

The separation and identification of different classes of metabolites requires multiple analytical techniques. Ion chromatography (IC) is an effective technique for separating polar metabolites as it uses both a polar stationary phase and a polar mob...

Improving Sample Preparation Workflow with Automated Evaporation

The Thermo Scientific™ Rocket™ Evaporator system automates theconcentration process following extraction using a Thermo Scientific™ Dionex™ ASE™ Accelerated Solvent Extractor system or a Thermo Scientific™ AutoTrace™ 280 Solid-Phase Extraction instru...

Hydraulic Fracturing Wastewaters

Wastewater produced from hydraulic fracturing (fracking) contains salts (anions and cations), metals, and radioisotopes that have been mobilized from the hydrocarbon-rich shale layer. When high-pressure is used to crack the shale, wastewater flows to...

What is the Role of a Next Generation Suppressor

Suppression technology is the heart of an ion chromatography (IC) system. Previous advances in suppressor functionality have focused on continuous operation, achieving high-capacity and ease-of-use. Advances in the future will continue to optimize th...

Accelerated Solvent Extraction for Bitumen Extraction from Oil Sands

Accelerated solvent extraction technique uses considerably less time and solvent per sample and has the potential to revolutionize bitumen extraction from oil sands in the heavy crude oil industry.

Accelerated Solvent Extraction for Monitoring Persistent Organic Pollutants in Ambient Air

Extraction of persistent organic pollutants from air sampling cartridges is an essential part of current air monitoring regulations. The accelerated solvent extraction technique has proven to yield equivalent results to the traditional Soxhlet proced...

WP: 708632: Use of Accelerated Solvent Extraction with In-Cell Cleanup to Eliminate Sample Cleanup During Sample Preparation

Accelerated solvent extraction is a sample preparation technique thatgreatly reduces the amount of time and solvent required to achieve analyte extraction. Use of accelerated solvent extraction with in-cell cleanup can eliminate the need to use gel p...

Highlighted Capillary IC Applications

Capillary IC systems provide true on-request 24/7 uptime with no equilibration necessary, taking performance and ease-of-use to a whole new level. These always ready systems can be used for various applications, including, but not limited to, environ...

Third Party Instrument Control with Chromeleon Chromatography Data System (CDS) Software (WP70885)

Over the last few decades chromatographic instrumentation and separations have become mainstream techniques for most laboratories. The main techniques are Gas Chromatography (GC) and High Performance Liquid Chromatography (HPLC). All these chromatogr...

How does the analysis of biomolecules benefit from UHPLC?

Ultra high performance liquid chromatography (UHPLC) provides improved separation speed, throughput, and sensitivity by employing stationary phase particles of around 2 μm or smaller. UHPLC has found widespread use in the analysis of small molecules ...

Miniaturization of Liquid Chromatography: Why Do We Do It?

Miniaturization of liquid chromatography (LC) is generally done to increase sensitivity, a necessity in proteomics to detect low abundant peptides and proteins. Other benefits of miniaturization include improving the efficiency of interfacing with ma...

AnalyteGuru

Knowledge Base Articles

Changes from EPA Method 218.6 to 218.7 Yield Improved Detection Limits for Hexavalent Chromium

LCGC Executive Summary: Multi-residue analysis of pesticides by GC-HRMS

Safety Assessment of Food Contact Materials: The Role of High-Resolution Mass Spectrometry in the Comprehensive Analysis of the Total Migrate

Analytical Challenges for Pesticide Residue Analysis in Food: Sample Preparation, Processing, Extraction and Cleanup

White Paper: Mass Spectral Studies of Polypropylene Chromatographic Well Plates

Extractables and Leachables: Regulatory requirements for vaccine and biologic products

Dr. John Koomen on Data-Independent Analysis and Targeted MS/MS Quantification of Biomarkers

Triumphs and Challenges of High-Resolution Mass Spectrometry in Comprehensive Pesticide Residue Screens

Pesticide Residue Analysis: Tips and Tricks for the Whole Workflow eBook

Determining Nitrosamines Using GC-MS/MS with Electron Ionization

Mass Spectral Studies of Polypropylene Chromatographic Well Plates

HRMS in Clinical Research: from Targeted Quantification to Metabolomics

The Power of High Resolution Accurate Mass Using Orbitrap Based GC-MS

Orbitrap Fusion MS for Glycan and Glycopeptide Analysis

Understanding New USP Chapter for Trace Elemental Contaminants in Dietary Supplements and Nutraceutical Products

Fast and Sensitive GC-MS/MS Analysis of Trace Chemicals

Accelerated Solvent Extraction for Additives in Polymer Materials

Improving Sample Preparation Workflow with Automated Evaporation

Measurement and Control of Copper Additives in Electroplating Baths by High-Performance Liquid Chromatography

Separation and Identification of Polar Metabolites by Ion Chromatography Coupled with High-Resolution Accurate-Mass Spectrometry

Improving Sample Preparation Workflow with Automated Evaporation

Hydraulic Fracturing Wastewaters

What is the Role of a Next Generation Suppressor

Accelerated Solvent Extraction for Bitumen Extraction from Oil Sands

Accelerated Solvent Extraction for Monitoring Persistent Organic Pollutants in Ambient Air

WP: 708632: Use of Accelerated Solvent Extraction with In-Cell Cleanup to Eliminate Sample Cleanup During Sample Preparation

Highlighted Capillary IC Applications

Third Party Instrument Control with Chromeleon Chromatography Data System (CDS) Software (WP70885)

How does the analysis of biomolecules benefit from UHPLC?

Miniaturization of Liquid Chromatography: Why Do We Do It?

Brands

Shopping Tools

eSolutions

Support

Thermo Fisher Scientific