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Knowledge Base Articles

Pushing the leading edge in protein analysis: Thermo Scientific Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer

BrochureUnderstanding biomolecules as drug targets, disease markers, and therapeutic agents demands highly sensitive analysis of complex biological samples, without sacrificing robustness and speed. The Thermo Scientific™ Q Exactive™ HF-X hybrid quad...

Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer - The Most Powerful Instrument Designed to Advance Your Scientific Pursuits

Orbitrap Fusion Lumos MS BrochurePUSHING NEW FRONTIERS IN SCIENCE Breakthroughs in science rely on great scientists making rapid progress answering challenging questions. “How does lipid metabolism affect cancer?” “How do non-cancerous cells mutate?”...

Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Drugs in Blood Samples

Gao M, Kozak M.ASMS 2015 PosterPurpose: To evaluate a benchtop quadrupole Orbitrap mass spectrometer for rapid quantitative analysis of immunosuppressant drugs in human blood samples for clinical research. Methods: Blood samples were processed by pro...

Variable Data-Independent Acquisition (vDIA) Delivers High Selectivity and Sensitivity in Combined Targeted and Untargeted Analyses for Small Molecules

Scheibner O, Kellmann M, Yang C, Bromirski M , TN-64283-LC-Veterinary-Drug-Residues-Muscle-Kidney-Milk-Plasma-TN64283Goal: Forty-four multi-class veterinary drugs of known concentrations were employed to demonstrate how the use of a generic variable ...

Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Meat, Plasma, and Milk on a Q Exactive Focus LC-MS System

Scheibner O, Bromirski MAN-614-LC-Veterinary-Drug-Residues-Meat-Products-Plasma-Milk-AN64249-ENGoal: To describe a new method for veterinary drug analysis, showing how the variable data-independent acquisition (vDIA) workflow achieves high sensitivit...

Versatile Solutions to Current Demands for Automated Sample Cleanup, High Throughput, and High-Resolution Chromatography on a Single LC-MS Platform

Lafontaine C, Murphy K, DiBussolo J.ASMS 2014 PosterUse of case studies to demonstrate the versatility of an LC-MS platform for research: high-throughput, online sample cleanup capabilities in a multi-channel UHPLC system coupled to a high-resolution...

Thermo Scientific Exactive Plus EMR Orbitrap LC-MS System: Sensitive identification, characterization, and quantification of intact proteins

Product BrochureWhile analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exacti...

Thermo Scientific Exactive Plus High Resolution MS for Quan/Qual analysis – A focus on quantification in clinical research labs

Rochat B, Bromirski M.WebinarFor the last decade, high-resolution mass spectrometers (HR-MS) have been associated with qualitative analyses while triple quadrupole MS (TQ-MS) have been associated with routine quantitative analyses. However, for an in...

Quantitation of Immunosuppressant Drugs in Blood Utilizing Second Generation Exactive High Resolution Accurate Mass Spectrometer and TraceFinder Software

Van Natta K, Kozak M, Nimkar S, Clarke W.ASMS 2012 PosterPurpose: Evaluate second generation Thermo Scientific Exactive™ high performance bench-top mass spectrometer for analysis of immunosuppressant drugs in whole blood for clinical research use onl...

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