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Knowledge Base Articles

Increased confidence of insect lipidome annotation from high-resolution Orbitrap LC/MSn analysis and LipidSearch software

David Peake1, Reiko Kiyonami1, Yasuto Yokoi2, Yelena Aldefinskaya3, Jeff Gilbert3, and Daniel Gachotte3APPLICATION NOTE 72942• Demonstrate the utility of LC/MS and data-dependent MSn acquisition for simultaneous lipid profiling and more complete lipi...

Pushing the leading edge in protein analysis: Thermo Scientific Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer

BrochureUnderstanding biomolecules as drug targets, disease markers, and therapeutic agents demands highly sensitive analysis of complex biological samples, without sacrificing robustness and speed. The Thermo Scientific™ Q Exactive™ HF-X hybrid quad...

Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer - The Most Powerful Instrument Designed to Advance Your Scientific Pursuits

Orbitrap Fusion Lumos MS BrochurePUSHING NEW FRONTIERS IN SCIENCE Breakthroughs in science rely on great scientists making rapid progress answering challenging questions. “How does lipid metabolism affect cancer?” “How do non-cancerous cells mutate?”...

Sheathless Capillary Electrophoresis Mass Spectrometry: Investigation Using High Resolution Accurate Mass MS for Metabolome Analysis

Wang J, Hudson JC, Conaway MP, Huang Y, Huhmer A.ASMS 2013 PosterMetabolomics is the comprehensive study of endogenous small molecule metabolites in biological samples. In the pharmaceutical context, understanding changes in the metabolome due to res...

Using HRAM Survey Analysis Combined with Rapid MS2 Data to Develop a Fragmentation Based Detection Workflow for Structure ID Acquisition

Stratton T, Ding C, Henrich C, Grensemann H, Pfaff H, Strohalm M, Kusch S.ASMS 2013 PosterPurpose: Demonstrate a workflow for metabolite detection and structure elucidation combining HRAM (high-resolution, accurate-mass) HCD MS2 with a new customizab...

Metabolomics Workshop

I Orbi 2012There are two major types of metabolite profiling studies: First is the study of the biotransformation of xenobiotic. But there is also the study of endogenous metabolite, or the so called Metabolomics/Metabonomics. While the application o...

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