Scientific Library
Access peer-reviewed scientific papers, application notes, technical guides, specification sheets, scientific posters, brochures, product support bulletins and so much more.
cancel
Showing results for 
Search instead for 
Did you mean: 

Knowledge Base Articles

Metabolomics as a Discovery Tool for Bioprospecting and Detection of Defense Compounds During Fungal Infection of Spruce Wood

Marit Almvik1, Marie-Pierre Pavageau, Nina Elisabeth Nagy2, Hans Ragnar Norli1, Ari Hietala2, Sven-Roar Odenmarck1, Monica Fongen3, Anas Kamleh4 Metabolomics 2019Every fourth tree in the Scandinavian forest is infected with rot. Root and butt rot fun...

Complete characterization of a lysine-linked antibody drug conjugate by native LC/MS intact mass analysis and peptide mapping

Aaron O. Bailey,1 Stephane Houel,1 Kai Scheffler,2 Eugen Damoc,3 Jennifer Sutton,1 Jonathan L. JosephsAPPLICATION NOTE 72511To perform complete characterization of the lysine-linked antibody drug conjugate (ADC) trastuzumab emtansine using both intac...

Full characterization of heterogeneous antibody samples under denaturing and native conditions on the Q Exactive BioPharma mass spectrometer

Kai Scheffler and Eugen DamocTo demonstrate the capabilities of the Thermo Scientific™ Q Exactive™ BioPharma mass spectrometry platform, particularly the High Mass Range (HMR) Mode for the characterization of antibody samples. The three different ope...

SelectScience Interview: Mass Spectrometry Inventor, Alexander Makarov, Explains How State-of-the-Art MS is Being Utilized in World Leading Anti-Doping Laboratories

Alexander MakarovSelectScience InterviewThe Hong Kong Jockey Club is one of the largest and most well respected flat racing organizations in the world. The Club has a world class drug-testing facility, on site at the Sha Tin Racecourse. This internat...

High-throughput untargeted screening of veterinary drug residues and metabolites in tilapia using high resolution orbitrap mass spectrometry

Wei Jia a, b *, Xiaogang Chu a, b, James Chang c, Perry G. Wang d, Ying Chen b, Feng Zhang bW. Jia, X. Chu, J. Chang, P.G. Wang, Y. Chen, F. Zhang, High-throughput untargeted screening of veterinary drug residues and metabolites in tilapia using high...

Development and Validation of a Qualitative Method for Target Screening of 448 Pesticide Residues in Fruits and Vegetables Using UHPLC/ESI Q‑Orbitrap Based on Data-Independent Acquisition and Compound Database

Jian Wang, Willis Chow, James Chang, Jon W. WongJ Agric Food Chem. 2017 Jan 18;65(2):473-493. doi: 10.1021/acs.jafc.6b05034. Epub 2017 Jan 5.A semiautomated qualitative method for target screening of 448 pesticide residues in fruits and vegetables wa...

A Nontargeted UHPLC-HRMS Metabolomics Pipeline for Metabolite Identification: Application to Cardiac Remote Ischemic Preconditioning

Judith Kouassi Nzoughet, Cinzia Bocca, Gilles Simard, Delphine Prunier-Mirebeau, Juan Manuel Chao de la Barca, Dominique Bonneau, Vincent Procaccio, Fabrice Prunier, Guy Lenaers,† and Pascal ReynierAnal. Chem. 2017, 89, 2138−2146In recent years, th...

Determination of Meat Authenticity Using a Comprehensive Targeted Proteomic Strategy and High-Resolution Mass Spectrometry

Orduna A, Beaudry F. Scientific PosterPurpose: Describe a sensitive, robust HRAM LC-MS method to detect and identify marker proteins in raw meat samples. Methods: Well-defined proteogenomic annotation, carefully selected surrogate tryptic peptides, a...

A robust and sensitive capillary flow LC – high-resolution accurate-mass MS platform for discovery and targeted proteomics

Alexander Boychenko1, Mike Baynham2, Stephan Meding1; Martin Ruehl1; Martin Samonig1; Remco Swart1International Hupo 2016We systematically investigated the effect of flow rate and column ID on MS sensitivity using samples with different complexity. T...

Top Contributors