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Knowledge Base Articles

SelectScience Interview: Mass Spectrometry Inventor, Alexander Makarov, Explains How State-of-the-Art MS is Being Utilized in World Leading Anti-Doping Laboratories

Alexander MakarovSelectScience InterviewThe Hong Kong Jockey Club is one of the largest and most well respected flat racing organizations in the world. The Club has a world class drug-testing facility, on site at the Sha Tin Racecourse. This internat...

Rapid Analysis of 25-Hydroxyvitamin D3, epi-25-Hydroxyvitamin D3, and 25-Hydroxyvitamin D2 in Plasma for Clinical Research Using High-Resolution Mass Spectrometry

Mindy Gao, James Goldberg, Thomas Carrell, and Marta Kozak Application Note 636Goal To quantify 25-hydroxyvitamin D3 and epi-25-hydroxyvitamin D3 along with 25-hydroxyvitamin D2 in human plasma for clinical research using high-resolution mass spectro...

Quantitation of 25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 in Plasma for Clinical Research Using an Affordable High-Resolution Mass Spectrometer

Mindy Gao, Marta Kozak.Application Note 634Goal To evaluate the performance of the Thermo Scientific™ Q Exactive™ Focus high-resolution Orbitrap mass spectrometer as a quantitative platform for HPLC-MS analysis of 25-hydroxyvitamin D metabolites in h...

Performing nanoLC doesn’t have to be wicked hard

Southwick KiOrbi 2014 Tips on key practices that will help make you successful with nLC. Information on nLC and column maintenance as well as suggestions to increase the robustness of nLC. Fisher ...

Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Drugs in Blood Samples

Gao M, Kozak M.ASMS 2015 PosterPurpose: To evaluate a benchtop quadrupole Orbitrap mass spectrometer for rapid quantitative analysis of immunosuppressant drugs in human blood samples for clinical research. Methods: Blood samples were processed by pro...

Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Animal Products Using a Novel Benchtop Orbitrap Mass Spectrometry System

Scheibner O, Bromirski M, Kellmann M, Westrup S, Yang C.AOAC 2015 Poster Note 71667Purpose: Fast and reliable analysis of veterinary drugs in various matrices. Methods: A generic UHPLC method was used in combination with full scan/vDIA data acquisiti...

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