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SelectScience Interview: Mass Spectrometry Inventor, Alexander Makarov, Explains How State-of-the-Art MS is Being Utilized in World Leading Anti-Doping Laboratories

Alexander MakarovSelectScience InterviewThe Hong Kong Jockey Club is one of the largest and most well respected flat racing organizations in the world. The Club has a world class drug-testing facility, on site at the Sha Tin Racecourse. This internat...

Organosulfates in Humic-like Substance Fraction Isolated from Aerosols at Seven Locations in East Asia: A Study by Ultra-High-Resolution Mass Spectrometry

Peng Lin, Jian Zhen Yu, Guenter Engling and Markus KalbererEnviron. Sci. Technol. 2012, 46, 13118−13127Humic-like substances (HULIS) in ambient aerosols collected at seven locations in East Asia were analyzed using electrospray ionization (ESI) cou...

Analysis of monoclonal antibody sequence and post-translational modifications by time-controlled proteolysis and tandem mass spectrometry

Lichao Zhang1, A. Michelle English1, Dina L. Bai1, Scott A. Ugrin1, Jeffrey Shabanowitz1, Mark M. Ross1, Donald F. Hunt1,2,* and Wei-Han Wang1Mol Cell Proteomics. 2015 Nov 29. pii: mcp.O115.056721Methodology for sequence analysis of ~150 kDa monoclon...

Performing nanoLC doesn’t have to be wicked hard

Southwick KiOrbi 2014 Tips on key practices that will help make you successful with nLC. Information on nLC and column maintenance as well as suggestions to increase the robustness of nLC.http://iconference.adobeconnect.com/p6m9b0mgxed/Thermo Fisher ...

F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.

Yumimoto K, Matsumoto M, Onoyama I, Imaizumi K, Nakayama KI.J Biol Chem. 2013 Oct 4;288(40):28488-502. doi: 10.1074/jbc.M113.465179. Epub 2013 Aug 16.Although identification of substrates for an enzyme is a key step in elucidation of its biological f...

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.

Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SA, Ruggles KV, Fenyo D, Kitchens RT, Li S, Olvera N, Dao F, Rodriguez H, Chan DW, Lie...

Immunodepletion Plasma Proteomics by TripleTOF 5600 and Orbitrap Elite/LTQ-Orbitrap Velos/Q Exactive Mass Spectrometers.

Jones KA, Kim PD, Patel BB, Kelsen SG, Braverman A, Swinton DJ, Gafken PR, Jones LA, Lane WS, Neveu JM, Leung HC, Shaffer SA, Leszyk JD, Stanley BA, Fox TE, Stanley A, Hall MJ, Hampel H, South CD, de la Chapelle A, Burt RW, Jones DA, Kopelovich L, Ye...

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways.

Burkhart JM, Vaudel M, Gambaryan S, Radau S, Walter U, Martens L, Geiger J, Sickmann A, Zahedi RP.Blood. 2012 Oct 11;120(15):e73-82. Antiplatelet treatment is of fundamental importance in combatting functions/dysfunction of platelets in the pathogene...

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