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Knowledge Base Articles

Profiling and annotation of flavonoids using a product iondependent MSn data acquisition method on a Tribrid Orbitrap mass spectrometer

Reiko Kiyonami1, Iwao Sakane2, Seema Sharma1, Graeme Mcalister1, Caroline Ding1 and Andreas Huhmer1Metabolomics 2018The untargeted profiling of flavonoids provides insights into their biological functions and potential health benefits for humans. How...

Pushing the leading edge in protein analysis: Thermo Scientific Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer

BrochureUnderstanding biomolecules as drug targets, disease markers, and therapeutic agents demands highly sensitive analysis of complex biological samples, without sacrificing robustness and speed. The Thermo Scientific™ Q Exactive™ HF-X hybrid quad...

GC-Orbitrap MS Technology for Pesticides Analysis

LCGC, Amadeo Fernandez-Alba Comprehensive testing for the presence of pesticide residues in food requires the application of both liquid chromatography (LC) and gas chromatography (GC) coupled to mass spectrometry. In particular, interest is growing ...

High-throughput untargeted screening of veterinary drug residues and metabolites in tilapia using high resolution orbitrap mass spectrometry

Wei Jia a, b *, Xiaogang Chu a, b, James Chang c, Perry G. Wang d, Ying Chen b, Feng Zhang bW. Jia, X. Chu, J. Chang, P.G. Wang, Y. Chen, F. Zhang, High-throughput untargeted screening of veterinary drug residues and metabolites in tilapia using high...

Development and Validation of a Qualitative Method for Target Screening of 448 Pesticide Residues in Fruits and Vegetables Using UHPLC/ESI Q‑Orbitrap Based on Data-Independent Acquisition and Compound Database

Jian Wang, Willis Chow, James Chang, Jon W. WongJ Agric Food Chem. 2017 Jan 18;65(2):473-493. doi: 10.1021/acs.jafc.6b05034. Epub 2017 Jan 5.A semiautomated qualitative method for target screening of 448 pesticide residues in fruits and vegetables wa...

Determination of Meat Authenticity Using a Comprehensive Targeted Proteomic Strategy and High-Resolution Mass Spectrometry

Orduna A, Beaudry F. Scientific PosterPurpose: Describe a sensitive, robust HRAM LC-MS method to detect and identify marker proteins in raw meat samples. Methods: Well-defined proteogenomic annotation, carefully selected surrogate tryptic peptides, a...

Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer - The Most Powerful Instrument Designed to Advance Your Scientific Pursuits

Orbitrap Fusion Lumos MS BrochurePUSHING NEW FRONTIERS IN SCIENCE Breakthroughs in science rely on great scientists making rapid progress answering challenging questions. “How does lipid metabolism affect cancer?” “How do non-cancerous cells mutate?”...

Discovery of Emerging Disinfection By-Products in Water Using Gas Chromatography Coupled with Orbitrap-based Mass Spectrometry

Cojocariu C, Postigo C, Richardson SD, Barcelo D, and Silcock P.Application Note 10490This work has shown the successful application of the Q Exactive GC system for the characterization of iodo-DBPs in disinfected water extracts. • A large number of ...

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