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Knowledge Base Articles

SelectScience Interview: Mass Spectrometry Inventor, Alexander Makarov, Explains How State-of-the-Art MS is Being Utilized in World Leading Anti-Doping Laboratories

Alexander MakarovSelectScience InterviewThe Hong Kong Jockey Club is one of the largest and most well respected flat racing organizations in the world. The Club has a world class drug-testing facility, on site at the Sha Tin Racecourse. This internat...

Performing nanoLC doesn’t have to be wicked hard

Southwick KiOrbi 2014 Tips on key practices that will help make you successful with nLC. Information on nLC and column maintenance as well as suggestions to increase the robustness of nLC.http://iconference.adobeconnect.com/p6m9b0mgxed/Thermo Fisher ...

Evaluation of mycotoxins and their metabolites in human breast milk using liquid chromatography coupled to high resolution mass spectrometry.

Rubert J, León N, Sáez C, Martins CP, Godula M, Yusà V, Mañes J, Soriano JM, Soler C.Anal Chim Acta. 2014 Apr 11;820:39-46. doi: 10.1016/j.aca.2014.02.009. Epub 2014 Feb 12.Humans can be exposed to mycotoxins through the food chain. Mycotoxins are ma...

Screening of plant and fungal metabolites in wheat, maize and animal feed using automated on-line clean-up coupled to high resolution mass spectrometry.

Ates E, Godula M, Stroka J, Senyuva H.Food Chem. 2014 Jan 1;142:276-84. doi: 10.1016/j.foodchem.2013.07.054. Epub 2013 Jul 19.A wide range of plant and fungal metabolites can occur in cereals and feed but only a limited number of target compounds are...

Introduction of solid-phase microextraction as a high-throughput sample preparation tool in laboratory analysis of prohibited substances

Boyacı E, Gorynski K, Rodriguez-Lafuente A, Bojko B, Pawliszyn J.Anal Chim Acta. 2014 Jan 27;809:69-81. A fully automated, high-throughput method based on thin-film solid-phase microextraction (SPME) and liquid chromatography-mass spectrometry was de...

Interlaboratory Comparison of a General Method To Screen Foods for Pesticides Using QuEChERs Extraction with High Performance Liquid Chromatography and High Resolution Mass Spectrometry.

Eitzer BD, Hammack W, Filigenzi M.J Agric Food Chem. 2013 Dec 20.An interlaboratory comparison of a multipesticide residue analytical method is reported. The goal of the comparison was to evaluate the potential for liquid chromatography/high resoluti...

Methods For Identification Of Known And Unknown Food Contact Materials By Means Of HPLC-High Resolution-Accurate Mass Spectrometry

Hollosi L, Godula M.RAFA 2013 PosterPackaging materials (PM) and nonintentionally added substances (NIAS) are currently one of the hottest research topics in food safety relevant applications. Current research especially focuses on identification of ...

Maximize glycan structural information

Thermo Scientific Guide to Glycan AnalysisGlycosylation is one of the most important post-translational modifications of eukaryotic cell proteins. Glycan-modified proteins are involved in a wide range of biological and physiological processes includi...

Rapid and simple neurotoxin-based distinction of Chinese and Japanese star anise by direct plant spray mass spectrometry.

Schrage M, Shen Y, Claassen FW, Zuilhof H, Nielen MW, Chen B, van Beek TA.J Chromatogr A. 2013 Jul 24.Ingestion of products containing Chinese star anise (Illicium verum) fruits contaminated or adulterated with Japanese star anise (Illicium anisatum)...

Identifying Qualitative and Quantitative Differences in Recombinants and Antibody Enrichments for IGF1 as Provided by Different Vendors and Different Preparations Using High-Resolution Mass Spectrometry

Prakash A, Krastins B, Peterman S, Sarracino D, Garces A, Athanas M, Sutton J, Oran P, Nelson R, Lopez M.HUPO 2012 PosterPurpose: To understand the differences in purity, sequence, length, structure and post-translational modifications (PTMs) of vari...

Multiresidue analytical method for the simultaneous determination of 72 micropollutants in aqueous samples with ultra high performance liquid chromatography-high resolution mass spectrometry

Wode F, Reilich C, van Baar P, Dünnbier U, Jekel M, Reemtsma T.J Chromatogr A. 2012 Dec 28;1270:118-26. A multiresidue method for the simultaneous quantification of 72 micropollutants in aqueous samples by ultra high performance liquid chromatography...

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