Over the last few decades chromatographic instrumentation and separations have become mainstream techniques for most laboratories. The main techniques are Gas Chromatography (GC) and High Performance Liquid Chromatography (HPLC). All these chromatographic instruments are now operated using a Chromatography Data System (CDS) for instrument control and data handling, which has developed significantly over the last three decades. Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data (CDS) System software was a pioneer of third party instrument control and has continued to be the market leader with multivendor control and provides Operational Simplicity™.