Mann M, Kulak NA, Nagaraj N, Cox J.
Mol Cell. 2013 Feb 21;49(4):583-90.
High-resolution mass spectrometry (MS)-based proteomics has progressed tremendously over the years. For model organisms like yeast, we can now quantify complete proteomes in just a few hours. Developments discussed in this Perspective will soon enable complete proteome analysis of mammalian cells, as well, with profound impact on biology and biomedicine.
http://www.sciencedirect.com/science/article/pii/S1097276513000932Max Planck Institute of Biochemistry, 82152 Martinsried, Germany; The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.