The Use of FAIMS to Separate Loperamide from PEG Prior to MS Analysis Using an LTQ XL

[steve-day]

It is common practice in pharmaceutical development to
conduct discovery phase pharmacokinetic (PK) studies. In
these studies, dosing vehicles such as Tween 80, PEG 400,
and methyl cellulose are used in high concentrations to
dissolve the test compounds in dose formulations.