on 05-01-201210:31 AM - edited on 10-15-202111:58 AM by AnalyteGuru
Wieghaus A, Makarov A, Froehlich U, Kellmann M, Denisov E, Lange O. Application Note 30162 Over the past three years the combination of Orbitrap technology with a linear ion trap has become an established platform for high resolution, accurate mass LC/MSn analysis. The high resolving power, mass accuracy and dynamic range of the Orbitrap analyzer allow rigorous characterization of complex mixtures even in the absence of precursor ion mass selection. We now describe the development of a non-hybrid mass spectrometer comprising of an atmospheric-pressure ion source (API) and a standalone Orbitrap mass analyzer.