Hornshaw MP, Griffiths WJ. Biotech International. 2010 Sept-Oct;14-17 Metabolomics is one of a number of new research areas which are evolving in the wake of the genomic revolution. It is now evident that to meet the major challenges in biomedical science, scientists need more information than the simple genetic blueprint of an organism (genome). There is also the need to better understand which proteins are expressed (proteome) and also the metabolites generated in the organism (metabolome). So the field of metabolomics has emerged, where the aim is to determine the complement of metabolites in a given cell type, tissue or body fluid. This is a daunting task requiring much ingenuity, high technology and hard work. This article will introduce the basic technology used in the field of metabolomics and will present some exciting new results.