on 01-29-201307:10 AM - edited on 10-15-202106:11 AM by AnalyteGuru
Marx V. Nat Methods. 2012 Dec 27;10:19-22. Understanding disease-related changes, for example, calls for reliable, quantitative
ways of assessing protein levels, and mass spectrometers are instruments able to nail that task. But the data from so-called discovery proteomics experiments in which mass spectrometry is used to identify a large number of proteins in a sample are not always useful to biologists. Enter targeted proteomics, in which the analysis focuses on a subset of proteins of interest in a sample—an approach that has been steadily gaining traction over the last few years.