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TMT10 TAILS Workflow for Identification and Quantitation of the N-terminome by Terminal Amino Isotope Labeling of Substrates

Team TFS
Team TFS
The N-terminal amino acid and its modification are known to have a major impact on protein stability and half-life. Proteolysis generates new protein N-termini, known as
neo N-termini, and is an essential post-translational modification significantly impacting the fate of a protein and those it interacts with. Consequently, proteases and their
substrates are an increasingly important domain of study in proteomics and drug development.
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Last update:
‎08-26-2014 03:50 PM
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