Structural Analysis of Native N-Glycans Released from Proteins Using a Novel Mixed-Mode Column and a Hybrid Quadrupole-Orbitrap Mass Spectrometer

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This application note compares two approaches for the structural characterization of N-glycans released from proteins. Analysis was carried out using a novel Thermo Scientific™ GlycanPac™ AXH-1 column and a Thermo Scientific™ Q Exactive™ hybrid quadrupole-Orbitrap™ mass spectrometer.