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Reputable Mentor II
Reputable Mentor II
Compton PD, Kelleher NL.
Nat Methods. 2012 Nov;9(11):1065-6.
The centrality of protein molecules in biological processes confers great importance to the study of their highly variable structures and functions. Mass spectrometry has found great utility in the study of protein primary structure. But although many cellular tasks are executed by individual proteins, much of the cellular machinery responsible for life processes is composed of noncovalently bound assemblies of multiple protein molecules. Because they are one level higher in the organizational hierarchy, protein complexes present additional experimental challenges.
Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
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