Endothall is a widely used herbicide for both terrestrial and aquatic weeds. Major uses of endothall include defoliation of cotton, the control of aquatic weeds and
algae, and as a dessicating agent for lucerne and potatoes. Human exposure to endothall in excess of the maximum contamination level (MCL) may cause gastrointestinal
problems. Endothall is regulated by the United States Environmental Protection Agency (EPA) with an MCL
at 0.1 mg/L or 100 ppb for drinking water;1 and the California EPA developed the Public Health Goal (PHG)
of 0.58 mg/L or 580 ppb for this compound.2