Van Natta K, Kozak M, He X.
Slide Presentation
Purpose: Evaluate Thermo Scientific Exactive Plus high performance bench-top mass spectrometer for drug screening of whole blood for forensic toxicology purposes.
Methods: Whole blood samples were processed by precipitation with ZnSO4/methanol. Samples were injected onto an HPLC under gradient conditions and detected on an Exactive Plus mass spectrometer. Results were analyzed with Thermo Scientific ExactFinder software.
Results: Over 300 drugs were detected at LODs ranging from 5-100 ng/mL in whole blood.
Thermo Fisher Scientific