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Screening of 300 Drugs in Blood Utilizing Second Generation Exactive Plus High-Resolution, Accurate Mass Spectrometer and ExactFinder Software

Reputable Mentor II
Reputable Mentor II
Van Natta K, Kozak M, He X.
Slide Presentation
Purpose: Evaluate Thermo Scientific Exactive Plus high performance bench-top mass spectrometer for drug screening of whole blood for forensic toxicology purposes. Methods: Whole blood samples were processed by precipitation with ZnSO4/methanol. Samples were injected onto an HPLC under gradient conditions and detected on an Exactive Plus mass spectrometer. Results were analyzed with Thermo Scientific ExactFinder software. Results: Over 300 drugs were detected at LODs ranging from 5-100 ng/mL in whole blood.

Thermo Fisher Scientific
Version history
Last update:
‎10-15-2021 08:54 AM
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