Despite advances in analytical detection technology achieving required limits of sensitivity, whilst maintaining reproducibility, can still be an issue for many bioanalytical laboratories. Traditional scale SPE helps to clean up the sample to minimize matrix effects, however in order to pre-concentrate the sample a lengthy dry down and reconstitution step needs to be employed. This process is not only time consuming but can have a detrimental effect on the recovery of the analyte due to volatility or non-specific binding.
By using Thermo Scientific™ SOLAμ™ a twenty-fold concentration of sample can be achieved without the need for a lengthy dry-down step, increasing sensitivity without compromising assay performance.
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