Derek J. Bailey, Graeme C. McAlister, Seema Sharma, Philip M. Remes, Ralf Tautenhahn, and Ioanna Ntai
ASMS 2018
Purpose: Real-time selection of optimal collision energy for compound fragmentation.
Methods: Perform a series of hidden, ion-trap scans to generate a breakdown curve
for each precursor and select the best energy for fragmentation during the proceeding
analytical scan.
Results: Optimal selection of collision energies in real-time helps improve data quality
while needing fewer analyses, increasing throughput, and reducing time spent
optimizing fragmentation settings for each compound.
Thermo Fisher Scientific, San Jose, CA, 95134
United States
