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Real-Time Collisional Energy Optimization on the Orbitrap Fusion Platform for Confident Unknown Identification

Reputable Mentor II
Reputable Mentor II
Derek J. Bailey, Graeme C. McAlister, Seema Sharma, Philip M. Remes, Ralf Tautenhahn, and Ioanna Ntai
ASMS 2018
Purpose: Real-time selection of optimal collision energy for compound fragmentation. Methods: Perform a series of hidden, ion-trap scans to generate a breakdown curve for each precursor and select the best energy for fragmentation during the proceeding analytical scan. Results: Optimal selection of collision energies in real-time helps improve data quality while needing fewer analyses, increasing throughput, and reducing time spent optimizing fragmentation settings for each compound.

Thermo Fisher Scientific, San Jose, CA, 95134
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Last update:
‎10-15-2021 11:20 AM
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