on 06-11-201205:50 AM - edited on 10-15-202110:12 AM by Closed Account
Crawford E, Bromirski M. Application Note 565 The combination of the ID-CUBE coupled to the Exactive high-resolution MS proved to be a rapid and robust tool for screening and fingerprint characterization. The Orbitrap platform provided extremely fast accurate-mass measurements of ❤️ ppm with external mass calibration for all of the analyses, and switching between the ESI source and the ID-CUBE source was very smooth, taking less than 3 minutes total. Optimization of the heating setting was achieved in less than one minute for rapid heating of the sample. Using the standardized OpenSpot sample cards, a single sample analysis could be completed in 10 seconds per card. Both liquids and powders were easily analyzed using the ID-CUBE source as shown in the experiments detecting sibutramine in Pai You Guo herbal weight loss aid. Dietary supplements could be quickly fingerprinted and characterized for quality control testing.