Rapid Determination of Benzalkonium Chloride in a Cosmetic

[steve-day]

This work describes an HPLC method with UV detection
for the rapid and sensitive determination of benzalkonium
chloride in cosmetic samples using an Acclaim Surfactant
Plus column with a phosphate buffer (pH 3)/CH3CN
mobile phase. The separation requires only 6 min and the
MDL of benzalkonium chloride is 1 μg/mL.