Gillette MA, Carr SA.
Nat Methods. 2013 Jan;10(1):28-34.
Targeted mass spectrometry (MS) is becoming widely used in academia and in pharmaceutical and biotechnology industries for sensitive and quantitative detection of proteins, peptides and post-translational modifications. Here we describe the increasing importance of targeted MS technologies in clinical proteomics and the potential key roles these techniques will have in bridging biomedical discovery and clinical implementation.
http://www.nature.com/nmeth/journal/v10/n1/pdf/nmeth.2309.pdfBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.