McHale K.
Slide Presentation
• The method is capable of easy confirmatory and quantitative analysis
of 46 illicit drugs at LOQs of 0.5 – 5 ng/mL in urine.
• Ultrahigh mass resolution of 50,000 FWHM provided the necessary
selectivity to identify 46 drugs in urine in 9 minutes with minimal sample
preparation
• Analyte confirmation is achieved by utilizing better than 5 ppm mass
accuracy with external mass calibration.
• Good quantitative accuracy achieved by isotopically-labeled standard.
• Nicotine example demonstrates the need for ≥50,000 resolution in
addition to exact masses.
Thermo Fisher Scientific
United States
