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Quantitative Screening of 46 Illicit Drugs in Urine using Exactive Ultrahigh Resolution and Accurate Mass system

Reputable Mentor II
Reputable Mentor II
McHale K.
Slide Presentation
• The method is capable of easy confirmatory and quantitative analysis of 46 illicit drugs at LOQs of 0.5 – 5 ng/mL in urine. • Ultrahigh mass resolution of 50,000 FWHM provided the necessary selectivity to identify 46 drugs in urine in 9 minutes with minimal sample preparation • Analyte confirmation is achieved by utilizing better than 5 ppm mass accuracy with external mass calibration. • Good quantitative accuracy achieved by isotopically-labeled standard. • Nicotine example demonstrates the need for ≥50,000 resolution in addition to exact masses.

Thermo Fisher Scientific
Version history
Last update:
‎10-15-2021 08:54 AM
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