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Reputable Mentor II
Reputable Mentor II
Van Natta K, Kozak M, Nimkar S, Clarke W.
ASMS 2012 Poster
Purpose: Evaluate second generation Thermo Scientific Exactive™ high performance bench-top mass spectrometer for analysis of immunosuppressant drugs in whole blood for clinical research use only utilizing the Thermo Scientific ClinSpec Immunosuppressant Test kit and samples previously analyzed by a clinically validated method on a triple stage quadrupole mass spectrometer. Methods: Whole blood samples were processed by precipitation with ZnSO4/ methanol. Samples were injected onto an HPLC under gradient conditions and detected on an Exactive Plus mass spectrometer. Results: Standards and controls from test kit passed all method parameters for linearity recovery. This method showed excellent correlation with a clinically validated triple stage quadrupole method.

Thermo Fisher Scientific
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Last update:
‎10-15-2021 09:42 AM
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