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Orbitrap_SciLib
Reputable Mentor II
Reputable Mentor II
Ahmed Mostafa1, Shelly Bonte-Gelok2, Charles Yang3, Jonathan Beck3, Dipankar Ghosh3, Paul Yang2
Application Note 645
Goal Develop an HRAM-based LC-MS/MS workflow to quantitatively analyze contaminants of emerging concern (CECs) in biosolids samples and to screen for 381 non-targeted CECs. Conclusion • A rapid dilute and shoot method for the quantitative determination of targeted CECs, such as endocrine disrupting chemicals, pharmaceuticals, personal care products, as well as their degradation by-products, has been developed. • Using ultrasonic-based sample preparation and HPLC-Orbitrap MS analysis without any sample cleanup, this method has been optimized for the determination of 49 CECs present in biosolids and terrestrial biomes exposed to biosolids-amended soils. • Semi-quantitative results showed the presence of surfactants, musks, and treatment by-products in biosolids. • Efforts to obtain analytical standards to complete the studies are on-going.


1 Department of Chemistry and Biology, Ryerson University, Toronto, Ontario, Canada 2 Ontario Ministry of the Environment, 125 Resources Road, Etobicoke, Ontario, Canada 3 Thermo Fisher Scientific, 355 River Oaks Parkway, San Jose, CA, USA
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‎10-15-2021 08:24 AM
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