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Proteomic Analysis Reveals Expression Differences in Escherichia coli Strains Associated with Persistent Versus Transient Mastitis

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Lippolis JD, Brunelle BW, Reinhardt TA, Sacco RE, Nonnecke BJ, Dogan B, Simpson K, Schukken YH.
ASMS 2013 Poster
Escherichia coli is a leading cause of bacterial mastitis in dairy cattle. Typically this infection is transient in nature, causing an infection that lasts 2‐3 days. However, in a minority of cases, E. coli has been shown to cause a persistent intramammary infection. The mechanisms that allow for a persistent E. coli infection are not fully understood. However, E. coli strains that cause persistent infections have been shown to be capable of surviving longer in mammary epithelial cell lines. The goal of this work is to determine protein expression differences in transient versus persistent E. coli strains isolated from infected dairy cattle.


Ruminant Diseases and Immunology Research Unit; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, ARS/USDA, Ames, Iowa.; Cornell University, College of Veterinary Medicine, Ithaca, New York.
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Last update:
‎10-15-2021 11:37 AM
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