PD Biomarker Measurement by LC/MS/MS – Resolving Sensitivity and Throughput Challenges Using High Resolution Mass Spectrometry

[Orbitrap_SciLib]

Sturm RM, Jones BR, Shan L, Buckholz JE, Biondolillo RF, Mulvana DE

To implement the EASY-Spray nano-electrospray ion source (Thermo Scientific, Inc.) for quantification of beta nerve growth factor (β-NGF) in human serum by immunoprecipitation combined with immunoaffinity liquid chromatography with high-resolution, accurate-mass spectrometry (LC-HRAM-MS/MS).


Q2 Solutions, a Quintiles Quest Joint Venture