Orbitrap Tribrid Series 3.4 Patch
With this patch, the polarity of the reagent used for calibrating IC Make-up flow and the fitting mechanism used to extract the optimum flow are modified. The calibration now uses the negative reagent ion species, which shows a much more pronounced maximum in flow pressure due to differences in the ionization process and leads to a more robust calibration. In addition, the optimum is now evaluated directly, as opposed to from a fit to the dataset, which on some instruments attempted to set a flow pressure in exceeding the flow controller maximum.
Thermo Fisher Scientific
United States
