Showing results for 
Search instead for 
Did you mean: 
Reputable Mentor II
Reputable Mentor II
David M Horn,1 Torsten Ueckert,2 Kai Fritzemeier,2 Katja Tham,2 Carmen Paschke,2 Frank Berg,2 Hans Pfaff,2 Xiaoyue Jiang,1 Shijun Li,1 and Dani Lopez-Ferrer

A new label-free quantification method based on the Minora algorithm is presented and compared to pre-existing label free quantification methods in the Thermo Scientific™ Proteome Discoverer™ software framework. The results of the new algorithm were significantly more accurate across a wide dynamic range compared to spectral counting and “Top N” quantification. The new algorithm was also run on a subset of the Akhilesh Pandey human proteome dataset to identify proteins specific to specific tissue types.

1Thermo Fisher Scientific, San Jose, CA, USA 2Thermo Fisher Scientific, Bremen, Germany
Version history
Last update:
‎10-15-2021 06:59 AM
Updated by: