on 10-08-201309:33 AM - edited on 10-15-202107:12 AM by AnalyteGuru
Hauschild JP, Denisov E, Peterson A, Lange O, Makarov A, Damoc E, Müller M, Scheffler K, Wieghaus A,Kellmann M HUPO 2013 Poster Purpose: Presenting technological and performance developments on the Thermo Scientific™ Q Exactive Plus™ bench-top quadrupole-Orbitrap™ mass spectrometer.
Methods: Using advanced quadrupole technology, comprising a hyperbolic segmented quadrupole, the transmission efficiency is drastrically increased. Recording longer transient signals on the Orbitrap mass analyzer doubles the resolving power. Intelligent gas control allows analysis of samples above 20 kDa, like intact proteins.
Results: In addition to nearly doubled transmission efficiency for precursor isolation, precursor isolation windows are rectified to further optimize new modes of operation, like data independent acquisition and pair-wise analysis.