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Orbitrap_SciLib
Reputable Mentor II
Reputable Mentor II
Cunniff J, Wang K, Eiserberg G, Stratton T, Comstock K
ASMS 2013 Poster Note
Purpose: Demonstrate a workflow for metabolite detection and structure elucidation by HRAM fragmentation-directed secondary analysis using multiple fragmentation techniques. Methods: Survey analysis of metabolism samples was performed by HRAM full scan and HCD MS2 analysis on a Thermo Scientific™ Q Exactive™ hybrid quadrupole- Orbitrap mass spectrometry. These analysis were processed using fragment ion searching (FISh) to detect structurally related components in the samples for acquistion of MSn data on a Thermo Scientific™ Velos Pro™, dual-pressure linear ion trap mass spectrometer utilizing a combination of HCD and CID fragmentation techniques. Results: Rapid Metabolite identification and structure elucidation


Thermo Fisher Scientific
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‎10-15-2021 11:27 AM
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