Monoclonal Antibody and Related Product Characterization under Native Conditions using a Benchtop Exactive Plus EMR MS

[Orbitrap_SciLib]

Xuan Y, Debaene F, Stojko J, Beck A, Dorsselaer AV, Cianferani S, Bromirski M.
ASMS 2014 Poster
Purpose: Demonstrate the characterization of mABs, antibody-drug conjugates (ADCs), mAb/antigen (MAb/Ag) complexes, and a mixture of mAbs under their native conditions by using a high-resolution, accurate-mass (HRAM) benchtop mass spectrometer with extended mass range (EMR).


Thermo Fisher Scientific, Institut Pluridisciplinaire Hubert Curien, University of Strasbourg, and Centre d'Immunologie Pierre Fabre, Saint Juliene En Genevois.