Monoclonal Antibody and Related Product Characterization Under Native Conditions Using a Benchtop Mass Spectrometer

[Orbitrap_SciLib]

Xuan Y, Debaene F, Stojko J, Beck A, Van Dorsselaer A, Cianférani S and Bromiski M
Application Note 597
Demonstrate the characterization of mAbs, antibody-drug conjugates (ADC), mAb/antigen (mAb/Ag) complexes, and a mixture of mAbs under their native conditions by using a high-resolution, accurate-mass (HRAM) benchtop mass spectrometer with extended mass range (EMR) in combination with a chip-based electrospray ionization interface.


Thermo Fisher Scientific