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claudia-bouman
Team TFS
Team TFS
Department of Medical Radiation Physics and Diagnostics, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764
International Journal of Mass Spectrometry (2011), V304, pp1–8, doi: 10.1016/j.ijms.2011.02.013
Method development for thermal ionization mass spectrometry in the frame of a biokinetic tracer study with enriched stable isotopes of zirconium
Matthias B. Greiter, Vera Höllriegl and Uwe Oeh
Isotope dilution in thermal ionization mass spectrometry (ID-TIMS) is a precise method for quantification of isotope ratios in geological samples, or for trace elements analysis in geological and environmental samples. This work presents an optimized ID-TIMS method for application in the field of life sciences,more precisely in the frame of a human biokinetic study on zirconium with oral and intravenous administration of two stable isotope tracers. The method allows analyzing simultaneously different stable zirconium isotopes (two isotopically enriched artificial tracers and the natural background) in human blood plasma and urine.
  • TIMS
  • Triton
  • Zr isotopes
  • Life sciences
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