Ingestion of toxin contaminated food (or food supplements) is responsible for a variety of aggressive, debilitating and often lethal diseases. Many of the toxins are highly modified amino acids or amines and include domoic acid (causing amnesic shellfish poisoning), b-N-oxalylamino- L-alanine (lathyrism), b-N-methylamino-L-alanine (Guam amyotrophic lateral sclerosis with secondary Parkinsonism and Alzheimer’s dementia), and anilides (toxic oil- or Spanish oilsyndrome).