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Maradolipids: Diacyltrehalose Glycolipids Specific to Dauer Larva in Caenorhabditis elegans

Reputable Mentor II
Reputable Mentor II
Penkov S, Mende F, Zagoriy V, Erkut C, Martin R, Pässler U, Schuhmann K, Schwudke D, Gruner M, Mäntler J, Reichert-Müller T, Shevchenko A, Knölker HJ, Kurzchalia TV.
Angew Chem Int Ed Engl. 2010 Dec 3;49(49):9430-5.
Don't stress: Maradolipids, are the first diacyltrehaloses found to be produced in animal organisms. The nematode Caenorhabditis elegans synthesizes maradolipids for the highly stress-resistant dauer larvae. Genetic knockout studies result in the improper morphology of the gut lumen of dauer larvae. Maradolipids might be important for understanding the chemical basis for the resistance of dauer larvae to extreme environmental stress.
Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany.
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