Glycoproteins of biological, diagnostic, or therapeutic
interest owe key aspects of their normal function to the
oligosaccharides attached to the protein backbone.
Changes in the number, type, composition, or linkage
pattern of these glycans may serve as a biomarker of
disease or influence the efficacy of a biotherapeutic
product.
1
For this reason, the ability to correctly
identify and measure these glycans is of scientific interest,
and to do so reliably, quickly, and inexpensively is of
practical benefit.
United States
