A liquid chromatography tandem mass spectrometry method for the analysis of paclitaxel in human serum has been developed. Using SOLA cartridges or plates, sample preparation is fast and reproducible giving excellent recovery levels. The analysis was carried out on an Accucore RP-MS 2.6 μm 50 × 2.1 mm HPLC column for a fast separation with a cycle time of 2 minutes while maintaining excellent peak shape.
United States
