LC-MS/MS Method for the Determination of HCTZ and Losartan from Human Plasma Using SOLA CX

[steve-day]

Thermo Scientific SOLA CX cartridges allow for faster
methods, more reproducible results and requires smaller
sample volumes than conventional loose-packed SPE
cartridges. Coupled with a Thermo Scientific Accucore aQ
column this allows the separation of losartan and HCTZ in
human plasma with good peak shape and sensitivity in two
minutes.